ZDHHC21 antibody (AA 131-240)

Catalog No. ABIN705566

The Rabbit Polyclonal anti-ZDHHC21 antibody is suitable to detect ZDHHC21 in samples from Rat. It has been validated for WB, IF (cc), IF (p), ELISA, IHC (p) and IHC (fro).

Quick Overview for ZDHHC21 antibody (AA 131-240) (ABIN705566)

Target: ZDHHC21 (Zinc Finger, DHHC-Type Containing 21 (ZDHHC21))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZDHHC21 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ZDHHC21 Antibody

Binding Specificity: AA 131-240

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZDHHC21

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZDHHC21

Target: ZDHHC21 (Zinc Finger, DHHC-Type Containing 21 (ZDHHC21))

Alternative Name: ZDHHC21

Background:

Synonyms: DNZ1, DHHC21, DHHC-21, HSPC097, 9130404H11Rik, Palmitoyltransferase ZDHHC21, Zinc finger DHHC domain-containing protein 21, ZDHHC21

Background: Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity).

Gene ID: 340481

UniProt: Q8IVQ6