MAL antibody (AA 65-153) (Biotin)

Catalog No. ABIN708133

This Rabbit Polyclonal antibody specifically detects MAL in ELISA, WB, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MAL antibody (AA 65-153) (Biotin) (ABIN708133)

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAL antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MAL Antibody (Biotin)

Binding Specificity: AA 65-153

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAL

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MAL

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Alternative Name: MAL

Background:

Synonyms: mal, MAL protein gene, Mal T-cell dferentiation protein, MAL_HUMAN, MALGENE, MPV17, Myelin and lymphocyte protein, T-cell dferentiation protein MAL, T-lymphocyte maturation-associated protein, VIP17.

Background: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, Jul 2008].

Gene ID: 4118

Pathways: Asymmetric Protein Localization