FAM89B antibody (AA 41-150) (Biotin)

Catalog No. ABIN720987

The Biotin-conjugated Rabbit Polyclonal anti-FAM89B antibody (ABIN720987) specifically detects FAM89B in ELISA, WB, IHC (fro) and IHC (p). The antibody is reactive with Human samples.

Quick Overview for FAM89B antibody (AA 41-150) (Biotin) (ABIN720987)

Target: FAM89B (Family with Sequence Similarity 89, Member B (FAM89B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM89B antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FAM89B Antibody (Biotin)

Binding Specificity: AA 41-150

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM89B/MMTV-R

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FAM89B

Target: FAM89B (Family with Sequence Similarity 89, Member B (FAM89B))

Alternative Name: FAM89B

Background:

Synonyms: Family with sequence similarity 89 member B, Mammary tumor virus receptor 2v Mammary turmor virus receptor homolog 1, MMTVR, MMTVR2, MTVR1, Protein FAM89B, FA89B_HUMAN.

Background: Mtvr1 is a 176 amino acid protein that exists as two alternatively spliced isoforms. Belonging to the FAM89 family, Mtvr1 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Gene ID: 23625