MAP1LC3A antibody

Catalog No. ABIN730973

The Rabbit Polyclonal anti-MAP1LC3A antibody is suitable to detect MAP1LC3A in samples from Human, Mouse and Rat. It has been validated for WB, IHC (p) and IF (p).

Quick Overview for MAP1LC3A antibody (ABIN730973)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP1LC3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MAP1LC3A Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAP1LC3A/MAP1A/MAP LC3 Alpha/Beta

Isotype: IgG

Application Details

Application Notes: WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Alternative Name: Map1lc3a

Background:

Synonyms: MAP1LC3A, MAP1a + MAP1b, microtubule-associated protein 1 light chain 3, Autophagy LC3, Microtubule-associated proteins 1A/1B light chain 3A, MAPLC3, MAP-LC3, Microtubule-associated protein 1 light chain 3 alpha, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modier LC3 A, MAP1 light chain 3-like protein 1.MAP1LC3A

Background: Microtubule-associated MAPILC3A constitutes nearly half of the mass of all the microtubule associated proteins that copurify with brain microtubules. MAP1LC3A is one of three human orthologs of the rat Map1LC3, (named MAP1LC3A, MAP1LC3B, and MAP1LC3C). The three isoforms of human MAP1LC3 exhibit distinct expression patterns in different human tissues and also differ in their post-translation modifications. MAP1LC3A and MAP1LC3C are produced by the proteolytic cleavage after the conserved C-terminal Gly residue, MAP1LC3B does not undergo C-terminal cleavage and exists in a single modified form.

Gene ID: 84557

Pathways: Autophagy