BAFF antibody (AA 221-309) (HRP)

Catalog No. ABIN740184

The HRP-conjugated Rabbit Polyclonal anti-BAFF antibody (ABIN740184) specifically detects BAFF in ELISA, IHC (p) and IHC (fro). The antibody is reactive with Human and Rat samples.

Quick Overview for BAFF antibody (AA 221-309) (HRP) (ABIN740184)

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAFF antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BAFF Antibody (HRP)

Binding Specificity: AA 221-309

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse BAFF

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Alternative Name: BAFF

Background:

Synonyms: ApoL related ligand TALL 1, B cell Activating Factor, B lymphocyte stimulator , BLYS, CD 257, CD257, CD257 antigen, delta BAFF, Dendritic cell derived TNF like molecule, DTL, DTL precursor, TALL 1, TALL1, THANK, TNF and APOL related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, TNF homolog that activates apoptosis NKFB and JNK, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, Tumor necrosis factor ligand superfamily member 20, Tumor necrosis factor like protein ZTNF4, Tumor necrosis factor superfamily member 13B, ZTNF4, TN13B_MOUSE .

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq].

Gene ID: 24099

UniProt: Q9WU72

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response