TNFSF14 antibody (AA 141-240) (PE)

Catalog No. ABIN740635

This Rabbit Polyclonal antibody specifically detects TNFSF14 in WB and FACS. It exhibits reactivity toward Mouse and Rat.It has been mentioned in 1 publication

Quick Overview for TNFSF14 antibody (AA 141-240) (PE) (ABIN740635)

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFSF14 antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-TNFSF14 Antibody (PE)

Binding Specificity: AA 141-240

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNFSF14

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-TNFSF14 antibody (PE) (ABIN740635)

Sibilano, Gaudenzio, DeGorter, Reber, Hernandez, Starkl, Zurek, Tsai, Zahner, Montgomery, Roers, Kronenberg, Yu, Galli: "A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice." in: Nature communications, Vol. 7, pp. 13696, (2016) (PubMed).

Target Details for TNFSF14

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Alternative Name: TNFSF14

Background:

Synonyms: LTg, TR2, CD258, HVEML, LIGHT, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, TNFSF14, UNQ391/PRO726

Background: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

Gene ID: 8740

UniProt: O43557

Pathways: Cancer Immune Checkpoints