CPI-17 antibody (pThr38)

Catalog No. ABIN753433

This Rabbit Polyclonal antibody specifically detects CPI-17 in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for CPI-17 antibody (pThr38) (ABIN753433)

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPI-17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CPI-17 Antibody

Binding Specificity: pThr38

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CPI17 alpha around the phosphorylation site of Thr38

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CPI-17

Target: CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))

Alternative Name: CPI17 alpha

Background:

Synonyms: 17 kDa PKC potentiated inhibitory protein of PP1, CPI 17 alpha, CPI 17, CPI 17alpha, CPI17, CPI-17, PKC potentiated inhibitory protein of PP1, PPP1INL, PPP1R14A, Protein phosphatase 1, Protein phosphatase 1 regulatory inhibitor subunit 14A, Protein phosphatase 1 regulatory subunit 14A, Regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, 17-KDa protein, 17 kDa PKC potentiated inhibitory protein of PP1, PKC potentiated inhibitory protein of PP1, PKC potentiated inhibitory protein of PP1, 17-KD, PP14A_HUMAN, Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD, Protein kinase C-potentiated inhibitor protein of 17 kDa, Protein phosphatase 1, Protein phosphatase 1 regulatory inhibitor subunit 14A, Regulatory subunit 14A.

Background: The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]

Gene ID: 94274