PHAP antibody (AA 41-140) (Cy5)

Catalog No. ABIN762180

The Cy5-conjugated Rabbit Polyclonal anti-PHAP antibody (ABIN762180) specifically detects PHAP in WB, IF (cc) and IF (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PHAP antibody (AA 41-140) (Cy5) (ABIN762180)

Target: PHAP (ANP32A/ANP32B) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A/B (ANP32A/ANP32B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHAP antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PHAP Antibody (Cy5)

Binding Specificity: AA 41-140

Specificity: Will recognize Acidic leucine-rich nuclear phosphoprotein 32 family member C,D, and E

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PHAP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PHAP

Target: PHAP (ANP32A/ANP32B) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A/B (ANP32A/ANP32B))

Alternative Name: PHAP

Background:

Synonyms: Acidic leucine-rich nuclear phosphoprotein 32 family member A, Acidic nuclear phosphoprotein pp32, pp32, Leucine-rich acidic nuclear protein, LANP, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Putative HLA-DR-associated protein I, PHAPI, ANP32A, C15orf1, MAPM, PHAP1

Background: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.

Gene ID: 8125

UniProt: P39687