RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) antibody

Antigen: RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1)

Synonyms: GAP, PKWS, RASA, CMAVM, CM-AVM, RASGAP, p120GAP, p120RASGAP, DKFZp434N071, D-RasGAP, RAS-GAP, RasGAP, DmelCG9209, CG9209

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)

Catalog no.: ABIN763466

Additional Information

Alternative name: RASGAP

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human RASGAP

Format: Lyophilized

Reconstitution: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotype: IgG  (Matching secondary antibodies)

Description: Synonym: GAP1M, GTPase activating protein of RAS, Ras GTPase activating protein 2, RAS p21 protein activator 2, RASA2.

Molecular Weight: 96kDa

Comments:

The Ras-related low molecular mass GTPases participate in signal transduction involving a variety of cellular functions

including cell-cycle progression

cellular differentiation

cytoskeletal organization

protein transport and secretion. The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein

p190

in growth factor stimulated and tyrosinekinase transformed cells. The RASGAP p190 complex may serve to couple Ras- and Rho-mediated signaling pathways. RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.

Application Details

Application Notes: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Concentration: 1mg/1ml

Purification: affinity purified by Protein A

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Storage: Ship at room temperature. Store at -20°C

Research Area: Cancer

Restrictions: For Research Use only