Reactivity: Various Species
ELISA, AP, IA
Host: Sheep
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
1.3mg/mL (OD280nm, E0.1% = 1.4)
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C .
Target
Progesterone 17-OH
Target Type
Hormone
Background
17-Hydroxyprogesterone (17-OH progesterone or 17OHP) is a C-21 steroid hormone produced during the synthesis of glucocorticoids and sex steroids. It is derived from progesterone via 17-hydroxylase, a P450c17 enzyme, or from 17-hydroxypregnenolone via 3-beta-hydroxysteroid dehydrogenase / Delta 5-4 isomerase. 17-Hydroxyprogesterone is a natural progestogen, and in pregnancy increases in the third trimester primarily due to fetal adrenal production. This hormone is primarily produced in the adrenal glands and to some degree in the gonads, specifically the corpus luteum of the ovary. Hydroxyprogesterone has been used for recurrent miscarriage and various menstrual disorders. Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that hydroxyprogesterone may reduce the risk of preterm delivery.Synonyms: 17-Hydroxyprogesterone, 17-alpha-Hydroxy-Progesterone, 17OHP