ZC3H12D antibody (C-Term)

Catalog No. ABIN783592

This Rabbit Polyclonal antibody specifically detects ZC3H12D in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for ZC3H12D antibody (C-Term) (ABIN783592)

Target: ZC3H12D (Zinc Finger CCCH-Type Containing 12D (ZC3H12D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3H12D antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ZC3H12D Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human ZC3H12D

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for ZC3H12D

Target: ZC3H12D (Zinc Finger CCCH-Type Containing 12D (ZC3H12D))

Alternative Name: ZC3H12D

Background: ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.Synonyms: C6orf95, MCP-induced protein 4, MCPIP4, TFL, Transformed follicular lymphoma, Zinc finger CCCH domain-containing protein 12D

Gene ID: 340152

NCBI Accession: NP_997243

UniProt: A2A288