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Zinc Finger Protein 346 (104116) (N-Term) antibody

Details for Product No. ABIN783747, Supplier: Login to see
Antigen
  • ZNF346
  • jaz
  • zfp346
  • JAZ
  • Zfp346
  • Jaz
  • Znf346
  • im:7136406
  • wu:fc21c04
  • zgc:158750
  • DsRBP-ZFa
  • ZFa
Epitope
N-Term
15
13
11
10
9
7
4
3
2
2
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
80
28
23
Host
Rabbit
73
7
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
67
32
13
11
10
4
3
1
1
1
1
1
Supplier
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Immunogen 20 amino acid peptide near the amino terminus of human ZNF346
Specificity This antibody detects ZNF346 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Alternative Name ZNF346 (104116 Antibody Abstract)
Background ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four C(2)H(2)-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.Synonyms: JAZ, Just another zinc finger protein, Zinc finger protein 346
Gene ID 23567
NCBI Accession NP_036411
UniProt Q9UL40
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA, Transcription Factors
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Zinc Finger Protein 346 (104116) (N-Term) antibody (ABIN783747) Western blot analysis of TRIP6 in EL4 cell lysate with TRIP6 antibody at 1 μg/ml.
Background publications Simpson, Wellenreuther, Poustka et al.: "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing." in: EMBO reports, Vol. 1, Issue 3, pp. 287-92, 2001 (PubMed).

Rosenfeld, Margalit: "Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs." in: Journal of biomolecular structure & dynamics, Vol. 11, Issue 3, pp. 557-70, 1994 (PubMed).