Zinc Finger Protein 346 (104116) (N-Term) antibody

Details for Product No. ABIN783747
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Synonyms ZNF346, jaz, zfp346, JAZ, Zfp346, Jaz, Znf346, im:7136406, wu:fc21c04, zgc:158750, DsRBP-ZFa, ZFa
(15), (13), (10), (9), (7), (4), (3), (2), (1), (1), (1), (1)
Human, Mouse (Murine), Rat (Rattus)
(73), (26), (20)
(67), (6)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(63), (30), (10), (10), (7), (4), (3), (3), (1), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Availability Will be delivered in 6 to 8 Business Days
Immunogen 20 amino acid peptide near the amino terminus of human ZNF346
Specificity This antibody detects ZNF346 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Alternative Name ZNF346 (104116 Antibody Abstract)
Background ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four C(2)H(2)-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.Synonyms: JAZ, Just another zinc finger protein, Zinc finger protein 346
Gene ID 23567
NCBI Accession NP_036411
UniProt Q9UL40
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Zinc Finger Protein 346 (104116) (N-Term) antibody (ABIN783747) Western blot analysis of TRIP6 in EL4 cell lysate with TRIP6 antibody at 1 μg/ml.
Background publications Simpson, Wellenreuther, Poustka et al.: "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing." in: EMBO reports, Vol. 1, Issue 3, pp. 287-92, 2001 (PubMed).

Rosenfeld, Margalit: "Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs." in: Journal of biomolecular structure & dynamics, Vol. 11, Issue 3, pp. 557-70, 1994 (PubMed).

Catalog No. ABIN783747
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