Endonuclease G antibody

Catalog No. ABIN783844

This Rabbit Polyclonal antibody specifically detects Endonuclease G in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Endonuclease G antibody (ABIN783844)

Target: Endonuclease G (ENDOG)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endonuclease G antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Endonuclease G Antibody

Specificity: This antibody recognizes ~35 kDa EndoG.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography

Immunogen: Synthetic peptide surrounding amino acid 280 of rat EndoG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.

Target Details for Endonuclease G

Target: Endonuclease G (ENDOG)

Alternative Name: Endonuclease G

Background: Endonuclease G (EndoG) is a mitochondrion-specific nuclease that specifically activated by apoptotic stimuli and translocates to the nucleus during apoptosis. In nucleus, EndoG induces nucleosomal fragmentation of DNA independent of caspase and DFF/CAD.Synonyms: ENDOG

Gene ID: 2021

NCBI Accession: NP_004426

UniProt: Q14249

Pathways: Apoptosis