Goat anti-Chimpanzee IgA (Free & Bound), (Secretory Component) Antibody
Quick Overview for Goat anti-Chimpanzee IgA (Free & Bound), (Secretory Component) Antibody (ABIN784371)
Target
Clonality
Application
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Binding Specificity
- Free & Bound, Secretory Component
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Reactivity
- Monkey, Chimpanzee
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Host
- Goat
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Purification
- Serum
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Immunogen
- Secretory component is present in monkey secretions bound to secretory IgA (sIgA) and in free form. Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65,000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. SC also has an affinity for polymeric IgM. Purified free secretory component isolated from pooled rhesus monkey milk is used for immunization. Freund's complete adjuvant is used in the first step of the immunization procedure.
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Restore with 1 mL sterile distilled water
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Buffer
- Without preservatives and foreign proteins.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
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- IgA
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Target Type
- Antibody
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Background
- Synonyms: Monkey Immunoglobulin A
Target
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