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Details for Product No. ABIN807922

CD16 (GRM1) antibody

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Antigen
Synonyms CD16, Fcgr3, Fcgr3a, FCGR3, FCGR3@
Reactivity
»Alternatives Human, Primate
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
Pubmed 6 references available
Catalog no. ABIN807922
Quantity 100 tests
Price
421.08 $   Plus shipping costs $45.00
Shipping to
Availability Please inquire for availability
Immunogen Human neutrophils
Clone 3G8
Isotype IgG1
Specificity The mouse monoclonal antibody 3G8 recognizes CD16, a low affinity receptor for aggregated IgG (FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA, 50-65 kDa, expressed on NK-cells, monocytes and macrophages) and CD16b (FcgammaRIIIB, 48 kDa, mainly expressed on neutrophils).
Alternative Name GRM1
Gene ID 2214
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Comment

CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)

Buffer The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Preservative Sodium azide
Storage 4 °C
Metes, Ernst, Chambers et al.: "Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene." in: Blood, Vol. 91, Issue 7, pp. 2369-80, 1998 (PubMed).

Zhu, Hamann, Muñoz et al.: "Intracellular expression of Fc gamma RIII (CD16) and its mobilization by chemoattractants in human eosinophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 5, pp. 2574-9, 1998 (PubMed).

Komano, Nanki, Hayashida et al.: "Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts." in: Arthritis research & therapy, Vol. 8, Issue 5, pp. R152, 2007 (PubMed).

Choi, Wang, Peterson et al.: "Use of an anti-CD16 antibody for in vivo depletion of natural killer cells in rhesus macaques." in: Immunology, Vol. 124, Issue 2, pp. 215-22, 2008 (PubMed).

Congy-Jolivet, Bolzec, Ternant et al.: "Fc gamma RIIIa expression is not increased on natural killer cells expressing the Fc gamma RIIIa-158V allotype." in: Cancer research, Vol. 68, Issue 4, pp. 976-80, 2008 (PubMed).

Burt, Plitas, Zhao et al.: "The lytic potential of human liver NK cells is restricted by their limited expression of inhibitory killer Ig-like receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 3, pp. 1789-96, 2009 (PubMed).

Alternatives for antigen "CD16 (GRM1)", type "Antibodies"
Hosts (200), (15), (1)
Reactivities (194), (24), (12), (11), (5), (1)
Applications (181), (67), (30), (28), (20), (17), (10), (6), (5), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Conjugates (30), (28), (24), (6), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Epitopes (2), (1), (1)
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