IDS antibody

Catalog No. ABIN2723275

The Mouse Monoclonal anti-IDS antibody is suitable to detect IDS in samples from Human. It has been validated for WB, IHC, IF and FACS.

Quick Overview for IDS antibody (ABIN2723275)

Target: IDS (Iduronate 2-Sulfatase (IDS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 3B10

Product Details anti-IDS Antibody

Characteristics: Homo sapiens iduronate 2-sulfatase (IDS), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human IDS(NP_000193) produced in HEK293T cell.

Isotype: IgG2a

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Alternative Name: IDS

Background: Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Molecular Weight: 59.2 kDa

Gene ID: 3423

NCBI Accession: NM_000202

HGNC: 3423

Pathways: Glycosaminoglycan Metabolic Process