IDS antibody

Catalog No. ABIN2723276

The Mouse Monoclonal anti-IDS antibody (Clone 4G2) (ABIN2723276) specifically detects IDS in WB, IHC, IF and FACS. The antibody is reactive with Human, Mouse, Rat, Dog and Monkey samples.

Quick Overview for IDS antibody (ABIN2723276)

Target: IDS (Iduronate 2-Sulfatase (IDS))

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This IDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 4G2

Product Details anti-IDS Antibody

Characteristics: Homo sapiens iduronate 2-sulfatase (IDS), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human IDS(NP_000193) produced in HEK293T cell.

Isotype: IgG2a

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Alternative Name: IDS

Background: Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Molecular Weight: 59.2 kDa

Gene ID: 3423

NCBI Accession: NM_000202

HGNC: 3423

Pathways: Glycosaminoglycan Metabolic Process