CTCF antibody

Catalog No. ABIN865482

The Mouse Monoclonal anti-CTCF antibody (Clone 1D11) (ABIN865482) specifically detects CTCF in WB and ELISA. The antibody is reactive with Human and Monkey samples.

Quick Overview for CTCF antibody (ABIN865482)

Target: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTCF antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1D11

Product Details anti-CTCF Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CTCF expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CTCF

Target: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Alternative Name: CTCF

Background: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Tissue specificity: Ubiquitous. Absent in primary spermatocytes. Synonyms: CTCF

Molecular Weight: 83kDa

Gene ID: 10664