NAC1 antibody (AA 519-523)

Catalog No. ABIN871752

The Rabbit Polyclonal anti-NAC1 antibody (ABIN871752) specifically detects NAC1 in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for NAC1 antibody (AA 519-523) (ABIN871752)

Target: NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NAC1 Antibody

Binding Specificity: AA 519-523

Specificity: The antibody detects endogenous levels of total NAC1 protein.

Purification: Affinity purified

Immunogen: Peptide sequence around AA 519-523 (A-G-P-S-A) derived from Human NAC1 Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Application Details

Application Notes: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for NAC1

Target: NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))

Alternative Name: NAC1

Background: Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.

Molecular Weight: 62 kDa

Gene ID: 112939

NCBI Accession: NP_443108

UniProt: Q96RE7