BCL2L1 antibody (N-Term)

Catalog No. ABIN925766

The Rabbit Polyclonal anti-BCL2L1 antibody is suitable to detect BCL2L1 in samples from Human, Mouse, Rat, Pig, Dog, Cow and Rabbit. It has been validated for WB.

Quick Overview for BCL2L1 antibody (N-Term) (ABIN925766)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivity: Human, Mouse, Rat, Pig, Dog, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCL2L1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Dog (Canine), Mouse (Murine), Rat (Rattus), Rabbit, Cow (Bovine), Pig (Porcine)

Immunogen: BCL2 L1 antibody was raised in rabbit using the N terminal of BCL2 1 as the immunogen

Application Details

Application Notes: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

BCL2L1 Blocking Peptide, (ABIN5612302), is also available for use as a blocking control in assays to test for specificity of this BCL2L1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Alternative Name: BCL2L1

Background: BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Synonyms: Polyclonal BCL2L1 antibody, Anti-BCL2L1 antibody, BCL2-like 1 antibody, BCL-XL/S antibody, BCL2L antibody, BCLX antibody, Bcl-X antibody, DKFZp781P2092 antibody, bcl-xL antibody, bcl-xS antibody.

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling