TNFSF13 antibody (Middle Region)

Catalog No. ABIN926638

This Rabbit Polyclonal antibody specifically detects TNFSF13 in WB. It exhibits reactivity toward Human.

Quick Overview for TNFSF13 antibody (Middle Region) (ABIN926638)

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFSF13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNFSF13 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: TNFSF13 antibody was raised in rabbit using the middle region of TNFSF13 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

TNFSF13 Blocking Peptide, (ABIN938064), is also available for use as a blocking control in assays to test for specificity of this TNFSF13 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TNFSF13

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Alternative Name: TNFSF13

Background: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified, such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. Synonyms: Polyclonal TNFSF13 antibody, Anti-TNFSF13 antibody, tumor necrosis factor, ligand superfamily, member 13 antibody, APRIL antibody, CD256 antibody, TALL2 antibody, TRDL-1 antibody, UNQ383/PRO715 antibody, ligand antibody.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response