VASP antibody (Middle Region)

Catalog No. ABIN926692

This Rabbit Polyclonal antibody specifically detects VASP in WB. It exhibits reactivity toward Human.

Quick Overview for VASP antibody (Middle Region) (ABIN926692)

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VASP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VASP Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: VASP antibody was raised in rabbit using the middle region of VASP as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

VASP Blocking Peptide, (ABIN935974), is also available for use as a blocking control in assays to test for specificity of this VASP antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for VASP

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Alternative Name: VASP

Background: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. Synonyms: Polyclonal VASP antibody, Anti-VASP antibody, vasodilator-stimulated phosphoprotein antibody.

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation