Amylin/DAP antibody (N-Term)

Catalog No. ABIN927970

This Rabbit Polyclonal antibody specifically detects Amylin/DAP in WB. It exhibits reactivity toward Human.

Quick Overview for Amylin/DAP antibody (N-Term) (ABIN927970)

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Amylin/DAP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Amylin/DAP Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: IAPP antibody was raised in rabbit using the N terminal of IAPP as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

IAPP Blocking Peptide, (ABIN5614120), is also available for use as a blocking control in assays to test for specificity of this IAPP antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Amylin/DAP

Target: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Alternative Name: IAPP

Background: Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. Synonyms: Polyclonal IAPP antibody, Anti-IAPP antibody, islet amyloid polypeptide antibody, AMYLIN antibody, DAP antibody, IAP antibody.

Pathways: Hormone Activity, Feeding Behaviour