HDAC3 antibody (C-Term)

Catalog No. ABIN928003

This Rabbit Polyclonal antibody specifically detects HDAC3 in WB. It exhibits reactivity toward Human and Rat.

Quick Overview for HDAC3 antibody (C-Term) (ABIN928003)

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HDAC3 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: Hdac3 antibody was raised in rabbit using the C terminal of Hdac3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Hdac3 Blocking Peptide, (ABIN937608), is also available for use as a blocking control in assays to test for specificity of this Hdac3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HDAC3

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Alternative Name: Hdac3

Background: Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation. Synonyms: Polyclonal Hdac3 antibody, Anti-Hdac3 antibody, histone deacetylase 3 antibody, Hdac3 antibody.

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development