TNFSF4 antibody (Middle Region)

Catalog No. ABIN929124

The Rabbit Polyclonal anti-TNFSF4 antibody (ABIN929124) specifically detects TNFSF4 in WB. The antibody is reactive with Human samples.

Quick Overview for TNFSF4 antibody (Middle Region) (ABIN929124)

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFSF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNFSF4 Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: TNFSF4 antibody was raised in rabbit using the middle region of TNFSF4 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TNFSF4 Blocking Peptide, (ABIN5616713), is also available for use as a blocking control in assays to test for specificity of this TNFSF4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TNFSF4

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Alternative Name: TNFSF4

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. Synonyms: Polyclonal TNFSF4 antibody, Anti-TNFSF4 antibody, tumor necrosis factor, ligand superfamily, member 4 antibody, CD134L antibody, CD252 antibody, GP34 antibody, OX-40L antibody, OX4OL antibody, TXGP1 antibody.

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints