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DNMT3B antibody

DNMT3B Reactivity: Human WB, FACS, ICC, DB Host: Mouse Monoclonal 2280C3a unconjugated
Catalog No. ABIN933161
  • Target See all DNMT3B Antibodies
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    Reactivity
    • 88
    • 57
    • 36
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 85
    • 5
    • 2
    • 1
    Mouse
    Clonality
    • 78
    • 15
    Monoclonal
    Conjugate
    • 38
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This DNMT3B antibody is un-conjugated
    Application
    • 81
    • 37
    • 29
    • 27
    • 15
    • 13
    • 11
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Dot Blot (DB)
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Cross-Reactivity (Details)
    Other species not studied.
    Purification
    Protein G affinity chromatography
    Immunogen
    DNMT3 B antibody was raised in mouse using recombinant Human Dna (Cytosine-5-)-Methyltransferase 3 Beta (Dnmt3 )
    Clone
    2280C3a
    Isotype
    IgG2b
    Top Product
    Discover our top product DNMT3B Primary Antibody
  • Application Notes
    WB: 0.2-2 µg/mL, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    DNMT3 B antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • Target
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    Alternative Name
    DNMT3B (DNMT3B Products)
    Synonyms
    DNMT3B antibody, LOC100218113 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MmuIIIB antibody, cb91 antibody, dnmt3bl antibody, dnmt7 antibody, sb:cb91 antibody, wu:fb16h07 antibody, DNA methyltransferase 3 beta antibody, DNA methyltransferase 3B antibody, DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a antibody, DNMT3B antibody, Dnmt3b antibody, dnmt3b antibody, dnmt3ba antibody
    Background
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. Synonyms: Monoclonal DNMT3B antibody, Anti-DNMT3B antibody, DNA (cytosine-5-)- methyltransferase 3 beta antibody, ICF antibody, M.HsaIIIB antibody.
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