Coagulation Factor VIIa (FVIIa) antibody

Antigen: Coagulation Factor VIIa (FVIIa)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Prothrombin Time (PT), Thrombin Generation Assay (TGA), Blocking Antibody (Inhibition), Indirect ELISA (iELISA)

Catalog no.: ABIN93506

Additional Information

Immunogen: recombinant human Factor VIIa (NovoSeven ® , Novo Nordisk A/S Denmark)

Format: Lyophilized

Description: Factor VIIa (FVIIa) is a key serine protease involved in the initiation of thecoagulation cascade. FVIIa requires tissue factor (TF), a membrane boundprotein, as an essential cofactor for maximal activity towards its biologicalsubstrates Factor X, Factor IX and Factor VII (FVII).

Specificity: Predicted reactivity: primates.

Application Details

Application Notes: Recommended Dilution 1: 15 000 (I-ELISA). Additional Information: no significant difference in binding to Factor VII and Factor VIIa .

Buffer: Affinity purified IgG in PBS pH 7.4

Storage: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior toopening them, to avoid any losses that might occur from liquid material adheringto the cap or sides of the tubes.

Research Area: Coagulation

Restrictions: For Research Use only