Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN93988

CD16 (GRM1) antibody

Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms CD16, Fcgr3, Fcgr3a, FCGR3, FCGR3@
»Alternatives Human, Primate
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP)
Pubmed 8 references available
Catalog no. ABIN93988
Quantity 0.1 mg
290.40 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 4 to 5 Business Days
Immunogen Normal human peripheral blood granulocytes
Clone LNK16
Isotype IgG1
Specificity The antibody LNK16 reacts with CD16, a low affinity receptor for aggregated IgG(FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA,50-65 kDa, expressed on NK-cells, monocytes and macrophages) and CD16b(FcgammaRIIIB, 48 kDa, mainly expressed on neutrophils).HLDA V, WS Code M MA069HLDA V, WS Code NK NK50
Purification Purified from hybridoma culture supernatant by protein A-affinity chromatography.
Purity > 95% (by SDS-PAGE)
Alternative Name GRM1
Background CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor.Human FcgammaRIII is expressed in two forms FcgammaRIII-A and -B. FcgammaRIII-A isa transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It isassociated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NKcell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-betasubunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE.FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and isinvolved in their activation and induction of a proadhesive phenotype.
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only
Concentration 1 mg/ml
Buffer Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
Preservative Sodium azide
Storage 4 °C
Mathison, Befus, Davison et al.: "Modulation of neutrophil function by the tripeptide feG." in: BMC immunology, Vol. 4, pp. 3, 2003 (PubMed).

Lin, Liu, Chen et al.: "CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features." in: Blood, Vol. 106, Issue 10, pp. 3567-74, 2005 (PubMed).

Congy-Jolivet, Bolzec, Ternant et al.: "Fc gamma RIIIa expression is not increased on natural killer cells expressing the Fc gamma RIIIa-158V allotype." in: Cancer research, Vol. 68, Issue 4, pp. 976-80, 2008 (PubMed).

Mathison, Christie, Davison: "The tripeptide feG inhibits leukocyte adhesion." in: Journal of inflammation (London, England), Vol. 5, pp. 6, 2008 (PubMed).

Chen, Freedman: "CD16+ gammadelta T cells mediate antibody dependent cellular cytotoxicity: potential mechanism in the pathogenesis of multiple sclerosis." in: Clinical immunology (Orlando, Fla.), Vol. 128, Issue 2, pp. 219-27, 2008 (PubMed).

Kahn, Moergelin, Shannon et al.: "Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response." in: PLoS pathogens, Vol. 4, Issue 9, pp. e1000149, 2008 (PubMed).

Meknache, Joensson, Laurent et al.: "Human basophils express the glycosylphosphatidylinositol-anchored low-affinity IgG receptor FcgammaRIIIB (CD16B)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 4, pp. 2542-50, 2009 (PubMed).

Mehrle, Watzl, von Lilienfeld-Toal et al.: "Comparison of phenotype of gammadelta T cells generated using various cultivation methods." in: Immunology letters, Vol. 125, Issue 1, pp. 53-8, 2009 (PubMed).

Alternatives for antigen "CD16 (GRM1)", type "Antibodies"
Hosts (200), (15), (1)
Reactivities (194), (24), (12), (11), (5), (1)
Applications (181), (67), (31), (28), (21), (17), (10), (6), (5), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Conjugates (30), (28), (24), (6), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Epitopes (2), (1), (1)