CYP39A1 antibody (C-Term)

Catalog No. ABIN951785

Product Details anti-CYP39A1 Antibody

Target: CYP39A1 (Cytochrome P450, Family 39, Subfamily A, Polypeptide 1 (CYP39A1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP39A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects endogenous levels of total Cytochrome P450 39A1 protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from Human Cytochrome P450 39A1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CYP39A1

Target: CYP39A1 (Cytochrome P450, Family 39, Subfamily A, Polypeptide 1 (CYP39A1))

Alternative Name: CYP39A1 (CYP39A1 Products)

Background: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.Synonyms: 24-hydroxycholesterol 7-alpha-hydroxylase, Cytochrome P450 39A1, Oxysterol 7-alpha-hydroxylase

Gene ID: 51302

NCBI Accession: NP_057677

Pathways: Monocarboxylic Acid Catabolic Process