NR1H3 antibody (Middle Region)
Quick Overview for NR1H3 antibody (Middle Region) (ABIN953747)
Target
See all NR1H3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 232-262, Middle Region
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Specificity
- This antibody reacts to NR1H3.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 232~262 amino acids from the Central region of human NR1H3
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Isotype
- Ig Fraction
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anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (Internal Region) antibody
NR1H3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 50-330) antibodyNR1H3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-387) antibodyNR1H3 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3E9 unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (C-Term) antibodyNR1H3 Reactivity: Human, Mouse, Rat, Cow, Xenopus laevis, Goat, Dog, Horse, Rabbit, Pig, Guinea Pig, Monkey, Zebrafish (Danio rerio), Bat, Hamster, Chicken WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-402) antibodyNR1H3 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (C-Term) antibodyNR1H3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 226-253) antibodyNR1H3 Reactivity: Human WB, FACS, IF Host: Rabbit Polyclonal RB23158 unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-402) antibodyNR1H3 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibodyNR1H3 Reactivity: Human, Mouse WB, ChIP-seq, ChIP Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 95-434) antibodyNR1H3 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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Alternative Name
- NR1H3
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Background
- NR1H3 form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs, see MIM 180245) and regulate expression of target genes containing LXR response elements.Synonyms: LXRA, Liver X receptor alpha, Nuclear orphan receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR-alpha
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Molecular Weight
- 50396 Da
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Gene ID
- 10062
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NCBI Accession
- NP_001123573
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
Target
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