TADA3L antibody (C-Term)

Catalog No. ABIN955062

Product Details anti-TADA3L Antibody

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Binding Specificity: AA 385-414, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TADA3L antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to TADA3L.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 385-414 amino acids from the C-terminal region of human TADA3L

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TADA3L

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Alternative Name: TADA3L (TADA3 Products)

Background: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].Synonyms: ADA3, ADA3 homolog, ADA3-like protein, STAF54, Transcriptional adapter 3-like

Molecular Weight: 48902 Da

Gene ID: 10474

NCBI Accession: NP_006345

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway