Transferrin antibody

Catalog No. ABIN955314

The Rabbit Polyclonal anti-Transferrin antibody (ABIN955314) specifically detects Transferrin in IP and ID. The antibody is reactive with Rat samples.

Quick Overview for Transferrin antibody (ABIN955314)

Target: Transferrin (TF)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transferrin antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunodiffusion (ID)

Product Details anti-Transferrin Antibody

Specificity: This antibody is directed against Rat Transferrin.

Purification: This IgG fraction was isolated from a high titer antiserum by salt fractionation and DEAE ion exchange chromatography. It was titered against its immunogens, sterile filtered, and analyzed for immunoglobulin purity and protein concentration.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 7.8 mg IgG/ml

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for Transferrin

Target: Transferrin (TF)

Background: Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergens from serum.Synonyms: Beta-1 metal-binding globulin, Serotransferrin, Siderophilin

Gene ID: 24825

NCBI Accession: NP_001013128

Pathways: Transition Metal Ion Homeostasis