ADAM17 antibody (AA 1-671)
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- Target See all ADAM17 Antibodies
- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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Binding Specificity
- AA 1-671
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ADAM17 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Specificity
- Recognizes human TACE. Minimal reactivity with BACE, ADAM8, -9, -10, and -15.
- Purification
- Immunoaffinity purified
- Immunogen
- Human TACE pure protein (EC domain 1-671aa).
- Isotype
- IgG
- Top Product
- Discover our top product ADAM17 Primary Antibody
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- Application Notes
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Approved: ELISA (1:10000 - 1:100000), Flo, WB (1 - 10 μg/mL)
Usage: Suitable for use in Western Blot, ELISA, Flow Cytometry. Western Blot: 1-10 μg/mL (ECL). ELISA: 1:10000-1:100000. Flow Cytometry: 500-1 μg/10^6 cells (blood lymphocytes or THP-1 cells). - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Sterile distilled water or PBS
- Concentration
- Lot specific
- Buffer
- lyophilized from PBS, 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Aliquot to Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.
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- Target
- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
- Alternative Name
- ADAM17 / TACE (ADAM17 Products)
- Background
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Name/Gene ID: ADAM17
Subfamily: Metallopeptidase M12B
Family: Protease
Synonyms: ADAM17, CD156B, CD156b antigen, CSVP, ADAM 17, NISBD, TNF-alpha converting enzyme, TNF-alpha convertase, TNF-alpha-converting enzyme, Snake venom-like protease, TACE - Gene ID
- 6868
- UniProt
- P78536
- Pathways
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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