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IFNG antibody (Interferon gamma)

Details for Product anti-IFNG Antibody No. ABIN964736, Supplier: Login to see
Antigen
  • IFNG2
  • IFN-g
  • Ifg
  • IFN-G
  • IFN-gamma
  • IFNG
  • IFG
  • IFI
Alternatives
anti-Cow (Bovine) IFNG antibody for Western Blotting
Reactivity
Cow (Bovine)
636
272
150
56
36
25
21
20
13
13
12
11
9
9
9
9
7
6
6
6
6
6
5
2
1
1
1
Host
Rabbit
546
395
173
35
8
7
4
4
2
Clonality
Polyclonal
Conjugate
This IFNG antibody is un-conjugated
159
115
63
46
36
12
10
10
9
6
5
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
650
571
364
125
125
117
75
61
48
41
38
38
37
32
31
17
15
9
9
8
7
7
7
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
Supplier
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Immunogen This protein A purified antibody was prepared prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to the 143 amino acids of the mature Bovine IFN Gamma protein.
Immunogen Type: RecombinantProtein
Isotype IgG
Specificity This product was protein A purified from monospecific antiserum by chromotography. This antibody is specific for bovine IFN gamma protein. A BLAST analysis was used to suggest cross-reactivity with IFN gamma from bovine and red deer sources based on 100% homology with the immunizing sequence. Cross-reactivity with IFN gamma from other sources has not been determined.
Characteristics Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.
Purification purified
Sterility Sterile filtered
Alternative Name Interferon Gamma (IFNG Antibody Abstract)
Background Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.
Synonyms: BoIFNG, IFN, Interferon gamma, IFNG
Gene ID 281237
NCBI Accession NP_776511
UniProt A9QXB7
Pathways Interferon-gamma Pathway
Application Notes This protein A purified antibody is suitable for ELISA and Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 16.9 kDa in size corresponding to bovine IFN gamma by western blotting in the appropriate cell lysate or extract.
Comment

Gene Name: IFN gamma

Restrictions For Research Use only
Format Liquid
Concentration 1.59 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store vial at 4° C prior to restoration.   For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  Expiration date is three (3) months from date of opening.
Expiry Date 3 months
Supplier Images
Western Blotting (WB) image for anti-IFNG antibody (Interferon gamma) (ABIN964736) Western blot using protein-A purified anti-bovine IFN gamma antibody shows detection ...
Product cited in: Schroder, Hertzog, Ravasi et al.: "Interferon-gamma: an overview of signals, mechanisms and functions." in: Journal of leukocyte biology, Vol. 75, Issue 2, pp. 163-89, 2004 (PubMed).