Apolipoprotein M (APOM) antibody

Antigen: Apolipoprotein M (APOM)

Synonyms: G3a, NG20, HSPC336, MGC22400, 1190010O19Rik, APOM, MGC128780, fb62d12, wu:fb62d12, g3a, ng20, hspc336, DKFZp469N144

Clonality: Monoclonal

Host: Please enquire

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Catalog no.: ABIN965578

Additional Information

Alternative name: ApoM

Gene ID: 55937

Isotype: IgG2a

Description: Apolipoprotein M (ApoM) is a member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. It is positively related to leptin. It is mainly expressed in liver and kidney. ApoM is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. It is important for the formation of prebeta-HDL and cholesterol efflux to HDL, and thereby inhibits formation of atherosclerotic lesions.

Specificity: TRX purified full length recombinant ApoM-GST expressed in E. Coli strain BL21 (DE3).

Application Details

Application Notes: Western Blot: 1: 500- 1: 1,000
IF: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Purification: Antibodies are purified by protein A affinity chromatography

Storage: Store at -20° C.

Restrictions: For Research Use only

Publications

Product: Xu, Dahlbäck: "A novel human apolipoprotein (apoM)." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31286-90, 1999 (PubMed).

Zhang, Jiao, Hurtig et al.: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." in: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, 2004 (PubMed).

Wolfrum, Poy, Stoffel: "Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis." in: Nature medicine, Vol. 11, Issue 4, pp. 418-22, 2005 (PubMed).