Apolipoprotein M (APOM) antibody

Details for Product No. ABIN965578
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Antigen
Synonyms APOM, fb62d12, wu:fb62d12, g3a, ng20, hspc336, G3a, HSPC336, NG20, apo-M, 1190010O19Rik
Reactivity
Human
(66), (32), (17), (15), (13), (12), (1)
Host
Please enquire
(45), (34), (10)
Clonality
Monoclonal
Conjugate
Un-conjugated
(8), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunofluorescence (IF), ELISA
(73), (54), (18), (16), (15), (13), (10), (7), (2), (2), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
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Catalog No. ABIN965578
481.25 $
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Isotype IgG2a
Specificity TRX purified full length recombinant ApoM-GST expressed in E. Coli strain BL21 (DE3).
Purification Antibodies are purified by protein A affinity chromatography
Alternative Name ApoM
Background Apolipoprotein M (ApoM) is a member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. It is positively related to leptin. It is mainly expressed in liver and kidney. ApoM is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. It is important for the formation of prebeta-HDL and cholesterol efflux to HDL, and thereby inhibits formation of atherosclerotic lesions.
Gene ID 55937
Application Notes Western Blot: 1: 500- 1: 1,000
IF: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Storage -20 °C
Product cited in: Xu, Dahlbäck: "A novel human apolipoprotein (apoM)." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31286-90, 1999 (PubMed).

Zhang, Jiao, Hurtig et al.: "Expression pattern of apolipoprotein M during mouse and human embryogenesis." in: Acta histochemica, Vol. 106, Issue 2, pp. 123-8, 2004 (PubMed).

Wolfrum, Poy, Stoffel: "Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis." in: Nature medicine, Vol. 11, Issue 4, pp. 418-22, 2005 (PubMed).

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