WD Repeat Domain 11 (WDR11) (N-Term) antibody

Antigen: WD Repeat Domain 11 (WDR11)

Synonyms: Brwd2, AW489876, MGC47139, mKIAA1351, 2900055P10Rik, WDR11, PHIP, BRWD2

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN965702

Additional Information

Alternative name: BRWD2

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human BRWD2 (Bromodomain and WD repeat-containing protein 2)

Description: BRWD2 (Bromodomain and WD repeat-containing protein 2) contains 9 WD repeats. WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly, BRWD2 typically contains a GH dipeptide 11-24 residues. BRWD2 (Bromodomain and WD repeat-containing protein 2) is a single-pass membrane protein. A chromosomal aberration involving BRWD2 is found in a form of glioblastoma. Translocation t(10,19)(q26,q13.3) with ZNF320.
Synonyms: KIAA1351, WDR11 (WD repeat-containing protein 11), WDR15 (WD repeat-containing protein 15)

Application Details

Restrictions: For Research Use only

Publications

Product: Nagase, Kikuno, Ishikawa et al.: "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 1, pp. 65-73, 2000 (PubMed).

Chernova, Hunyadi, Malaj et al.: "A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells." in: Oncogene, Vol. 20, Issue 38, pp. 5378-92, 2001 (PubMed).

Nakajima, Okazaki, Yamakawa et al.: "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 9, Issue 3, pp. 99-106, 2002 (PubMed).

Daub, Olsen, Bairlein et al.: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).