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ABL1 antibody

ABL1 Reactivity: Human, Mouse IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN965709
  • Target See all ABL1 Antibodies
    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
    Reactivity
    • 225
    • 135
    • 97
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 308
    • 3
    Rabbit
    Clonality
    • 308
    • 3
    Polyclonal
    Conjugate
    • 111
    • 18
    • 17
    • 15
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 9
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ABL1 antibody is un-conjugated
    Application
    • 212
    • 143
    • 143
    • 121
    • 66
    • 54
    • 33
    • 32
    • 19
    • 17
    • 10
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificity
    C-Abl (Ab-412) antibody detects endogenous levels of total c-Abl protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from human c-Abl around the phosphorylation site of tyrosine 412 (D-T-YP-T-A).
    Top Product
    Discover our top product ABL1 Primary Antibody
  • Application Notes
    IHC: 1:50-1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Kawai, Nie, Yuan: "Inactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6079-88, (2002) (PubMed).

    Yoshida, Komatsu, Wang, Kufe: "c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3292-300, (2002) (PubMed).

    Sionov, Coen, Goldberg, Berger, Bercovich, Ben-Neriah, Ciechanover, Haupt: "c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination." in: Molecular and cellular biology, Vol. 21, Issue 17, pp. 5869-78, (2001) (PubMed).

    Kharbanda, Pandey, Yamauchi, Kumar, Kaneki, Kumar, Bharti, Yuan, Ghanem, Rana, Weichselbaum, Johnson, Kufe: "Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage." in: Molecular and cellular biology, Vol. 20, Issue 14, pp. 4979-89, (2000) (PubMed).

  • Target
    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
    Alternative Name
    C-Abl (ABL1 Products)
    Pathways
    Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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