C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) antibody

Details for Product No. ABIN965709
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Antigen
Synonyms ABL1, ABL, CABL, ABLL, cb272, JTK7, bcr/abl, c-ABL, p150, v-abl, AI325092, Abl, E430008G22Rik, c-Abl, MTP
Reactivity
Human, Mouse (Murine)
(513), (334), (276), (180), (169), (156), (60), (48), (4), (1), (1)
Host
Rabbit
(508), (20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(25), (22), (22), (17), (17), (17), (17), (17), (17), (17), (17), (8), (8), (8)
Application
Immunohistochemistry (IHC)
(310), (171), (170), (136), (108), (50), (26), (20), (15), (12), (11), (7), (3), (2)
Pubmed 4 references available
Quantity 100 μg
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Catalog No. ABIN965709
398.75 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human c-Abl around the phosphorylation site of tyrosine 412 (D-T-YP-T-A).
Specificity C-Abl (Ab-412) antibody detects endogenous levels of total c-Abl protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name C-Abl
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Kawai, Nie, Yuan: "Inactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6079-88, 2002 (PubMed).

Yoshida, Komatsu, Wang et al.: "c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3292-300, 2002 (PubMed).

Sionov, Coen, Goldberg et al.: "c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination." in: Molecular and cellular biology, Vol. 21, Issue 17, pp. 5869-78, 2001 (PubMed).

Kharbanda, Pandey, Yamauchi et al.: "Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage." in: Molecular and cellular biology, Vol. 20, Issue 14, pp. 4979-89, 2000 (PubMed).

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