Daf-2 antibody (C-Term)

Catalog No. ABIN965970

This anti-Daf-2 antibody is a Rabbit Polyclonal antibody detecting Daf-2 in IHC. Suitable for C. elegans.

Quick Overview for Daf-2 antibody (C-Term) (ABIN965970)

Target: Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))

Reactivity: C. elegans

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (IHC)

Product Details anti-Daf-2 Antibody

Binding Specificity: C-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Caenorhabditis elegans daf-2(Abnormal dauer formation protein 2)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Daf-2

Target: Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))

Alternative Name: Daf-2

Background: The daf-2 is an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decreases in DAF-2 signaling induce metabolic and developmental changes, as in mammalian metabolic control by the insulin receptor. Decreased DAF-2 signaling also causes an increase in life-span. Lifespan regulation by insulin-like metabolic control is analogous to mammalian longevity enhancement induced by caloric restriction, suggesting a general link between metabolism, diapause, and longevity.