EHV-1 GP2 (C-Term) antibody

Catalog No. ABIN966048

Product Details

Target: EHV-1 GP2

Binding Specificity: C-Term

Reactivity: Equine Herpes Virus 1 (ESV-1)

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Wild-type equine herpesvirus 1 (EHV-1) glycoprotein, gp2

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References

Agerholm, Klas, Damborg, Borel, Pedersen, Christoffersen: "A Diagnostic Survey of Aborted Equine Fetuses and Stillborn Premature Foals in Denmark." in: Frontiers in veterinary science, Vol. 8, pp. 740621, (2021) (PubMed).

Smith, Kahan, Rorex, von Einem, Osterrieder, OCallaghan: "Expression of the full-length form of gp2 of equine herpesvirus 1 (EHV-1) completely restores respiratory virulence to the attenuated EHV-1 strain KyA in CBA mice." in: Journal of virology, Vol. 79, Issue 8, pp. 5105-15, (2005) (PubMed).

von Einem, Wellington, Whalley, Osterrieder, OCallaghan, Osterrieder: "The truncated form of glycoprotein gp2 of equine herpesvirus 1 (EHV-1) vaccine strain KyA is not functionally equivalent to full-length gp2 encoded by EHV-1 wild-type strain RacL11." in: Journal of virology, Vol. 78, Issue 6, pp. 3003-13, (2004) (PubMed).

Learmonth, Love, Gilkerson, Wellington, Whalley: "Inoculation with DNA encoding the glycoprotein gp2 reduces severity of equine herpesvirus 1 infection in a mouse respiratory model." in: Archives of virology, Vol. 148, Issue 9, pp. 1805-13, (2003) (PubMed).

Target Details

Target: EHV-1 GP2

Target Type: Viral Protein

Background: Wild-type equine herpesvirus 1 (EHV-1) strains express a large (250-kDa) glycoprotein, gp2, that is encoded by EUs4 (gene 71) located within the unique short region of the genome. The expression of full-length gp2 restore full respiratory virulence to the attenuated strain.