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Details for Product No. ABIN966077

EPH Receptor B6 (EPHB6) antibody

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Antigen
Synonyms Cekl, Mep, HEP, CEK9, EPHB5
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Pubmed 2 references available
Catalog no. ABIN966077
Quantity 0.1 mg
Price
536.25 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen Purified recombinant fragment of EphB6 expressed in E. Coli.
Clone 8E7H12
Isotype IgG1
Purification Purified
Alternative Name EphB6
Background EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.
Synonyms: HEP, MGC129910, MGC129911
Gene ID 2051
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Buffer PBS
Preservative Sodium azide
Storage 4 °C
Product cited in: Matsuoka, Obama, Kelly et al.: "Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration." in: The Journal of biological chemistry, Vol. 280, Issue 32, pp. 29355-63, 2005 (PubMed).

Ogawa, Wada, Okada et al.: "EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases." in: Journal of cell science, Vol. 119, Issue Pt 3, pp. 559-70, 2006 (PubMed).

Alternatives for antigen "EPH Receptor B6 (EPHB6)", type "Antibodies"
Hosts (40), (17), (4), (2)
Reactivities (60), (32), (30), (18), (17)
Applications (43), (32), (20), (17), (17), (10), (8), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (5), (3), (3), (2), (2), (1), (1), (1)
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