anti-EPH Receptor B6 antibody (EPHB6)

Details for Product anti-EPHB6 Antibody No. ABIN966077
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Synonyms CEK9, EPHB5, Cekl, Mep, HEP
(120), (37), (30), (1), (1), (1)
(94), (24), (6), (2)
Clonality (Clone)
Monoclonal ()
This EPH Receptor B6 antibody is un-conjugated
(7), (7), (7), (6), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
(100), (73), (58), (22), (16), (14), (10), (9), (5), (2), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Immunogen Purified recombinant fragment of EphB6 expressed in E. Coli.
Clone 8E7H12
Isotype IgG1
Purification Purified
Alternative Name EphB6 (EPHB6 Antibody Abstract)
Background EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.
Synonyms: HEP, MGC129910, MGC129911
Gene ID 2051
Pathways RTK Signaling
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Buffer PBS
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Ogawa, Wada, Okada et al.: "EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases." in: Journal of cell science, Vol. 119, Issue Pt 3, pp. 559-70, 2006 (PubMed).

Matsuoka, Obama, Kelly et al.: "Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration." in: The Journal of biological chemistry, Vol. 280, Issue 32, pp. 29355-63, 2005 (PubMed).

Catalog No. ABIN966077
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