EPH Receptor B6 antibody (AA 601-750)

Catalog No. ABIN1724689

Product Details anti-EPH Receptor B6 Antibody

Target: EPH Receptor B6 (EPHB6)

Binding Specificity: AA 601-750

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogen: Purified recombinant fragment of EphB6 (aa601-750) expressed in E. coli.

Clone: 2A6B9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-EPH Receptor B6 antibody (ABIN1724689)

Luo, Yu, Wu, Wu: "EphB6 crosslinking results in costimulation of T cells." in: The Journal of clinical investigation, Vol. 110, Issue 8, pp. 1141-50, (2002) (PubMed).

Target Details for EPH Receptor B6

Target: EPH Receptor B6 (EPHB6)

Abstract: EPHB6 Products

Background:

Description: EhpB6: EPH receptor B6. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

Aliases: HEP, EPHB6

Gene ID: 2051

HGNC: 2051

Pathways: RTK Signaling, Hormone Transport