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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Chromosome 14 Open Reading Frame 1 (C14orf1) (N-Term) antibody
|Synonyms||ERG28, NET51, homolog of yeast ergosterol28, T27I1.5, T27I1_5, C7H14orf1|
Mouse (Murine), Human
Alternatives Immunohistochemistry (IHC)
|3 references available|
|Price||316.25 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 5 to 7 Business Days|
|Immunogen||Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse ERG28(Probable ergosterol biosynthetic protein 28)|
|Description||ERG28(Probable ergosterol biosynthetic protein 28) has a role as a scaffold to help anchor ERG25, ERG26 and ERG27 to the endoplasmic reticulum. ERG28 may also be responsible for facilitating their interaction. The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). ERG28 acts as a scaffold to tether ERG27 and other 4,4-demethylation-related enzymes, forming a demethylation enzyme complex, in the endoplasmic reticulum. ERG28 interacts with ERG25, ERG26 and ERG27. It also interacts with ERG1, ERG3, ERG5, ERG6 and ERG11.|
|Application Notes||ELISA, Western blotting: 1µg/ml for 2hrs.|
|Purification||Purified by antigen-specific affinity chromatography.|
|Buffer||This antibody is stored in PBS, 50% glycerol|
|Preservative||0.01% Sodium Azide|
|Storage||Store at -20°C.|
|Research Area||Signaling, Metabolism|
|Restrictions||For Research Use only|
Mo, Valachovic, Randall et al.: "Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 15, pp. 9739-44, 2002 (PubMed).
Ghaemmaghami, Huh, Bower et al.: "Global analysis of protein expression in yeast." in: Nature, Vol. 425, Issue 6959, pp. 737-41, 2003 (PubMed).
Mo, Valachovic, Bard: "The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p)." in: Biochimica et biophysica acta, Vol. 1686, Issue 1-2, pp. 30-6, 2004 (PubMed).