HSPX (N-Term) antibody

Antigen: HSPX

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mycobacterium tuberculosis (M. tuberculosis )

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN966323

Additional Information

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Bacteria Mycobacterium tuberculosis HSPX (heat shock protein hspX)

Description: HSPX (heat shock protein hspX) functions as stress protein induced by anoxia. hspX has a proposed role in maintenance of long-term viability during latent, asymptomatic infections, and a proposed role in replication during initial infection. regulated by the two component regulatory system devr|rv3133c/devs|rv3132c, in response to a hypoxic signal. The hspX contains a ACD_sHsps-like domain. Alpha-crystallin domain (ACD) of alpha-crystallin- type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD).

Application Details

Restrictions: For Research Use only

Publications

Product: Cole, Brosch, Parkhill et al.: "Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." in: Nature, Vol. 393, Issue 6685, pp. 537-44, 1998 (PubMed).

Garnier, Eiglmeier, Camus et al.: "The complete genome sequence of Mycobacterium bovis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 13, pp. 7877-82, 2003 (PubMed).