Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 1 (SLC16A1) (N-Term) antibody

Antigen: Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 1 (SLC16A1)

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine), Rat (Rattus)

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN966547

Additional Information

Alternative name: Mct1

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Mct1 (Monocarboxylate transporter 1)

Description: Mct1 (Monocarboxylate transporter 1) functions as a Proton-linked monocarboxylate transporter. Mct1 (Monocarboxylate transporter 1) catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Mct1 (Monocarboxylate transporter 1) is a multi-pass membrane protein. Major isoform present in tumor cells, erythrocytes. Mct1 belongs to the major facilitator superfamily and Monocarboxylate porter (TC 2.A.1.13) family.
Synonyms: Slc16a1 (Solute carrier family 16 member 1)

Application Details

Restrictions: For Research Use only

Publications

Product: Carpenter, Poole, Halestrap: "Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function." in: Biochimica et biophysica acta, Vol. 1279, Issue 2, pp. 157-63, 1996 (PubMed).

Koehler-Stec, Simpson, Vannucci et al.: "Monocarboxylate transporter expression in mouse brain." in: The American journal of physiology, Vol. 275, Issue 3 Pt 1, pp. E516-24, 1998 (PubMed).

Collins, Yu, Coba et al.: "Proteomic analysis of in vivo phosphorylated synaptic proteins." in: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 5972-82, 2005 (PubMed).

Lee, Xu, Chen et al.: "Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 4, pp. 669-76, 2007 (PubMed).

Villén, Beausoleil, Gerber et al.: "Large-scale phosphorylation analysis of mouse liver." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 5, pp. 1488-93, 2007 (PubMed).

Zhou, Ye, Dong et al.: "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis." in: Journal of proteome research, Vol. 7, Issue 9, pp. 3957-67, 2008 (PubMed).