DOK2 antibody

Details for Product No. ABIN966763
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Antigen
Synonyms DokR, Frip, Dok-2, p56DOK, p56dok-2
Reactivity
Human
(134), (67), (49), (48), (41), (38), (24), (2)
Host
Rabbit
(127), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(88), (42), (40), (33), (32), (25), (7), (5)
Pubmed 3 references available
Quantity 100 µg
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Catalog No. ABIN966763
385.00 $
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p56Dok-2 around the phosphorylation site of tyrosine 299 (G-E-YP-A-V).
Specificity P56Dok-2 (Ab-299) antibody detects endogenous levels of total p56Dok-2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name p56Dok-2
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Cong, Yuan, Goff: "Characterization of a novel member of the DOK family that binds and modulates Abl signaling." in: Molecular and cellular biology, Vol. 19, Issue 12, pp. 8314-25, 2000 (PubMed).

Lemay, Davidson, Latour et al.: "Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling." in: Molecular and cellular biology, Vol. 20, Issue 8, pp. 2743-54, 2000 (PubMed).

Schaeper, Gehring, Fuchs et al.: "Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses." in: The Journal of cell biology, Vol. 149, Issue 7, pp. 1419-32, 2000 (PubMed).

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