Endogenous Retrovirus Group K, Member 10 (ERVK-10) antibody

Details for Product No. ABIN966889
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Antigen
Synonyms PR, Protease, Proteinase
Reactivity
Human
(2)
Host
Mouse
(2)
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
(2), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN966889
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Immunogen Purified recombinant fragment of PR expressed in E. Coli.
Clone 2F12B4-2F12H2
Isotype IgG1
Purification Ascitic fluid
Alternative Name PR
Background PR(progesterone receptor), with 933-amino acid protein (about 110kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
Synonyms: PR, NR3C3, PGR
Gene ID 5241
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: McGuire: "Prognostic factors in primary breast cancer." in: Cancer surveys, Vol. 5, Issue 3, pp. 527-36, 1987 (PubMed).

Bach: "Markets in kidneys." in: Lancet, Vol. 2, Issue 8411, pp. 1102, 1984 (PubMed).

Wen, Xu, Mais et al.: "The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8356-64, 1994 (PubMed).

Hagen, Silva, Amorim et al.: "Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys)3 ligands." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 5, Issue 4, pp. 527-34, 2000 (PubMed).

Jowett: "Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." in: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, 2000 (PubMed).

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