Rab 3D antibody

Antigen: Rab 3D

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine)

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN966928

Additional Information

Immunogen: Polyclonal antibody produced in rabbits immunizing with whole purified recombinant protein of human Rab 3D

Description: Members of the Rab 3 subfamily of low-molecular-mass GTP-binding proteins have been functionally implicated in regulated exocytosis. Rab 3D mRNA is predominantly expressed in white adipose tissue and, coincident with GLUT4, increases upon differentiation of 3T3-L1 -broblasts into insulin-responsive adipocytes [19]. Rab 3D displays close structural similarities with Rab 3A, an isoform which has been functionally implicated in regulated exocytosis in various cell types.

Application Details

Restrictions: For Research Use only

Publications

Product: Caswell, Spence, Parsons et al.: "Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments." in: Developmental cell, Vol. 13, Issue 4, pp. 496-510, 2007 (PubMed).

Curie, Sacco, Bussy et al.: "Impairment of cerebello-thalamo-frontal pathway in Rab-GDI mutated patients with pure mental deficiency." in: European journal of medical genetics, Vol. 52, Issue 1, pp. 6-13, 2009 (PubMed).