SET Domain, Bifurcated 1 (SETDB1) antibody
| Antigen | SET Domain, Bifurcated 1 (SETDB1) |
| Synonyms | ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, AU022152, MGC90670, mKIAA0067, SETDB1, NV10069, fc07d03, wu:fc07d03, si:ch211-81a5.6 |
| Clonality | Monoclonal (5H6D4) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human, Monkey, Mouse (Murine) |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Western Blotting (WB), ELISA |
 |
3 references available |
| Catalog no. | ABIN967016 |
| Quantity | 0.1ml (Variants) |
| Price | 426.25 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 5 to 7 Business Days |
Additional Information
| Alternative name | SETDB1 |
| Gene ID | 9869 |
| Immunogen | Purified recombinant fragment of human SETDB1 expressed in E. Coli. |
| Isotype | IgG1 |
| Clone | 5H6D4 |
| Description |
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-Lmethionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Tissue specificity: Widely expressed. High expression in testis. Synonyms: ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, SETDB1 |
| Molecular Weight | 180kDa |
Application Details
| Application Notes |
Western Bloting: 1/500 - 1/2000. ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test. |
| Purification | Ascitic fluid |
| Preservative | 0.03% sodium azide. |
| Storage | Store at 4°C, for long term storage, store at -20°C. |
| Restrictions | For Research Use only |
Publications
| Product |
Gevaert, Staes, Van Damme et al.: "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC." in: Proteomics, Vol. 5, Issue 14, pp. 3589-99, 2005 (PubMed).
Rosendorff, Sakakibara, Lu et al.: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, 2006 (PubMed). Gao, Yu, Bi et al.: "Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression." in: Molecular and cellular biochemistry, Vol. 305, Issue 1-2, pp. 35-44, 2007 (PubMed). |
Alternatives
Alternatives for antigen "SET Domain, Bifurcated 1 (SETDB1)", type "Antibodies"
| Hosts | Rabbit (35), Mouse (12) |
| Reactivities | Human (46), Mouse (Murine) (30), Rat (Rattus) (20), Cow (Bovine) (18), Dog (Canine) (18), Horse (Equine) (18), Pig (Porcine) (18), Rabbit (18), Sheep (Ovine) (18), Monkey (8) |
| Applications | Western Blotting (WB) (30), ELISA (29), Immunofluorescence (IF) (21), Immunohistochemistry (IHC) (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1) |
| Conjugates | Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1) |
| Epitopes | C-Term (3), AA 1058-1075 (2), N-Term (2), AA 475-489 (1) |
