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Details for Product No. ABIN967016

SET Domain, Bifurcated 1 (SETDB1) antibody

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Antigen
Synonyms ESET, H3-K9-HMTase4, KG1T, KMT1E, TDRD21, AU022152, mKIAA0067, SETDB1, NV10069, fc07d03, wu:fc07d03, si:ch211-81a5.6
Reactivity
»Alternatives Human, Monkey, Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), ELISA
Pubmed 3 references available
Catalog no. ABIN967016
Quantity 0.1 mL
Price
426.25 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days

Product details

Target Details Application Details Handling References Alternatives back to top
Immunogen Purified recombinant fragment of human SETDB1 expressed in E. Coli.
Clone 5H6D4
Isotype IgG1
Purification Ascitic fluid

Target Details

Application Details Handling References Alternatives back to top
Alternative Name SETDB1
Background This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-Lmethionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression.
Tissue specificity: Widely expressed. High expression in testis.
Synonyms: ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, SETDB1
Molecular Weight 180kDa
Gene ID 9869

Application Details

Target Details Handling References Alternatives back to top
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Target Details Application Details References Alternatives back to top
Preservative Sodium azide
Storage 4 °C

References

Target Details Application Details Handling Alternatives back to top
Product cited in: Gevaert, Staes, Van Damme et al.: "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC." in: Proteomics, Vol. 5, Issue 14, pp. 3589-99, 2005 (PubMed).

Rosendorff, Sakakibara, Lu et al.: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, 2006 (PubMed).

Gao, Yu, Bi et al.: "Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression." in: Molecular and cellular biochemistry, Vol. 305, Issue 1-2, pp. 35-44, 2007 (PubMed).

Alternatives

Target Details Application Details Handling References back to top
Alternatives for antigen "SET Domain, Bifurcated 1 (SETDB1)", type "Antibodies"
Hosts (33), (17)
Reactivities (50), (24), (14), (12), (12), (12), (8)
Applications (40), (28), (10), (7), (6), (4), (4), (4), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (2), (2), (2), (1), (1), (1)
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