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Details for Product No. ABIN967461

Interferon gamma (IFNG) antibody

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Antigen
Synonyms IFG, IFI, Ifg, IFN-g, IFNG2, IFN-gamma, IFN-G
Reactivity
»Alternatives Mouse (Murine)
Host
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Neutralization (Neut), Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN967461
Quantity 0.1 mg
Price
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Immunogen Mouse IFN-gamma
Clone XMG1-2
Isotype IgG1, kappa
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Purity Purified
Alternative Name IFN-gamma
Background The XMG1.2 antibody reacts with mouse interferon-gamma (IFN-gamma) protein. IFN-gamma is a pleiotropic cytokine, of approximately 15-17 kDa, involved in the regulation of the immune response. It plays an important role in activation, growth, and differentiation of T and B lymphocytes, macrophages, NK cells and other non-hematopoietic cell types. IFN-gamma production is associated with the Th-1 differentiation. This is a neutralizing antibody
Research Area Cytokines
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml
Buffer Aqueous buffered solution.
Preservative Sodium azide
Storage 4 °C
Abrams, Roncarolo, Yssel et al.: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992 (PubMed).

Cherwinski, Schumacher, Brown et al.: "Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies." in: The Journal of experimental medicine, Vol. 166, Issue 5, pp. 1229-44, 1987 (PubMed).

Sander, Höidén, Andersson et al.: "Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining." in: Journal of immunological methods, Vol. 166, Issue 2, pp. 201-14, 1994 (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996 (PubMed).

Alternatives for antigen "Interferon gamma (IFNG)", type "Antibodies"
Hosts (311), (178), (105), (23), (6), (3), (2), (1)
Reactivities (360), (165), (84), (27), (25), (17), (10), (10), (9), (8), (8), (8), (6), (4), (4), (4), (4), (4), (3), (1), (1), (1)
Applications (386), (305), (178), (72), (65), (60), (51), (37), (35), (30), (29), (28), (25), (17), (12), (11), (8), (7), (6), (6), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Conjugates (85), (51), (24), (11), (9), (6), (5), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (1)
Epitopes (9), (9), (6), (3), (3), (2), (2), (2), (2), (1), (1)
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