Glutamate-Ammonia Ligase (GLUL) (AA 1-373) antibody
|Synonyms||glul, MGC64262, GS, GLNS, PIG43, PIG59, Glns, GLUL, MGC128403, xgs, F15E12.14, F15E12_14, GLUTAMINE SYNTHETASE|
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
|5 references available|
|Price||Product not available in this region.|
|Alternative name||Glutamine Synthetase|
|Immunogen||Sheep Glutamine Synthetase|
|Cross-Reactivity||Rat (Rattus), Human, Mouse (Murine)|
|Description||Glutamine synthetase catalyzes the amination of glutamic acid to form glutamine. It is found in mammals as an octamer of identical 45 kDa subunits. Glutamine synthetase activity is a useful marker for astrocytes and an important differentiation feature in retina. It is also considered to be a key enzyme in the recycling of the neurotransmitter glutamate. This antibody is routinely tested by western blot analysis.|
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
|Molecular Weight||45 kDa|
Related Products: ABIN968545, ABIN967389
|Purification||Purified from tissue culture supernatant or ascites by affinity chromatography.|
|Buffer||Aqueous buffered solution containing BSA, glycerol.|
|Preservative||0.09% Sodium azide.|
|Storage||Store undiluted at -20° C.|
|Research Area||Neurology, Alzheimer's Disease, Amino Acids, Enzymes, Metabolism|
|Restrictions||For Research Use only|
Kentroti, Baker, Lee et al.: "Platelet-activating factor increases glutamine synthetase activity in early and late passage C-6 glioma cells." in: Journal of neuroscience research, Vol. 28, Issue 4, pp. 497-506, 1991 (PubMed).
Vardimon, Fox, Cohen-Kupiec et al.: "Expression of v-src in embryonic neural retina alters cell adhesion, inhibits histogenesis, and prevents induction of glutamine synthetase." in: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5275-84, 1991 (PubMed).
Fei, DAmbrosio, Li et al.: "Association of insulin receptor substrate 1 with simian virus 40 large T antigen." in: Molecular and cellular biology, Vol. 15, Issue 8, pp. 4232-39, 1995 (PubMed).
Labow, Souba, Abcouwer: "Glutamine synthetase expression in muscle is regulated by transcriptional and posttranscriptional mechanisms." in: The American journal of physiology, Vol. 276, Issue 6 Pt 1, pp. E1136-45, 1999 (PubMed).
Kronfeld, Kazimirsky, Lorenzo et al.: "Phosphorylation of protein kinase Cdelta on distinct tyrosine residues regulates specific cellular functions." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35491-8, 2000 (PubMed).